| Alzheimer's Disease Round areas of Injury in brain tissue are called Plaques click here to see Alzheimer plaques |
| BRASILIAN LYME LIKE ILLNESS 2 articles from Dr Yoshinari Click here for article ONE Click here for Article TWO Note: pictures of an Erythema migrans like lesion are presented. Spirochetes are illustrated. The species is yet to be determined |
| Borrelia DNA inside of Alzheimer Plaques Click here |
| Spirochetal Forms ( Cystic and Filamentous)inside nerve cells in Alzheimer Hippocampus tissue Click on the Images |
Treponema
Pallidum Buds,
Granules, and
Cysts as found in
Human Syphilitic
Chancres and seen
in Fixed unstained
smears observed
under dark ground
illumination
Coutts,
W.,E., and
Coutts, W.R.
American Journal
of Syphilis,
Gonorrhea and
Venereal Dis
37: 29-36,
1953
This Landmark
Article from Drs
Coutts in 1952
describes
Cystic
forms of Treponema
pallidum, with Buds
and Granular forms
in serum taken
from Syphilitic Chancres.
The authors survey the
previous literature dating
back to Schaudinn and
Hoffman, and cite the
views of many other
distinguished
syphilologists endorsed
the view that Pathogenic
spirochetes have a
complex
life cycle which
includes
vegetative (
spiral) and
diverse cystic and
granular forms.
To View
Coutts
Article Click
here
Pallidum Buds,
Granules, and
Cysts as found in
Human Syphilitic
Chancres and seen
in Fixed unstained
smears observed
under dark ground
illumination
Coutts,
W.,E., and
Coutts, W.R.
American Journal
of Syphilis,
Gonorrhea and
Venereal Dis
37: 29-36,
1953
This Landmark
Article from Drs
Coutts in 1952
describes
Cystic
forms of Treponema
pallidum, with Buds
and Granular forms
in serum taken
from Syphilitic Chancres.
The authors survey the
previous literature dating
back to Schaudinn and
Hoffman, and cite the
views of many other
distinguished
syphilologists endorsed
the view that Pathogenic
spirochetes have a
complex
life cycle which
includes
vegetative (
spiral) and
diverse cystic and
granular forms.
To View
Coutts
Article Click
here
| Stari Illness Dr Ed Masters Clinical photos of Erythema Migrans and Micrographs of the Spirochetes Click here to read original article |
| Comparison of Alzheimer disease Round Plaques with Tertiary Syphilis Infection of human Brain with Round Plaques Identical to Alzheimer Round plaques Click here to See Round Plaques in Syphilis Brain |
Click here for Transfection Click here for 1995
Publication describing Borrelia DNA transfected to
Human chromosome 11qpublication
Publication describing Borrelia DNA transfected to
Human chromosome 11qpublication
| Syphilis Plaques Match Alzheimer plaques slick here Both plaques in Brain are caused by Spirochetal infection |
| Round areas of brain injury [ Click here to see images] are called Plaques in two Dementia conditions 1. Alzheimer's disease 2. Syphilis ( General Paresis) Rounded profiles of Spirochetes (i.e.) CYSTIC forms cause the Plaques |
| Website Statement of Purpose Why are there so many Images and So Little Text ?? Click Here to Read Statement |
| MANY PROFILES OF BORRELIA CLICK HERE TO SEE ATLAS |
| Infectious Alzheimer's - Discussion of evidence from Animal inoculation studies Nature magazine November 2006Click here for link to the article |
| Spirochetes inside of nerve cells Harvard McLean Hospital Brain Bank tissue Images - used in Molecular Interrogation study for DNA of Borrelia Alzheimer Disease hippocampal Click here |
| Lyme disease in Spinal fluid at Stony Brook Med Ctr followed 8 years later by death from Alzheimer's - case study |
| Borrelia and Alzheimer's disease Lecture With all powerpoint slides -Philadelphia 2005 ILADS National Scientific Meeting -Click HERE |
| Powerpoint slide show - 72 images "Borrelia and Dementia, Medical Hypothesis" Columbia LDA National Scientific Meeting, Philadelphia , Penn October 20, 2006 Images - Click here - Adobe format Analysis of Pathology of Alzheimer's disease under the microscope - with connections established to DNA of Borrelia burgdorferi Flagellin DNA - Specifically staining Alzheimer plaques and GVB of Alzheimer's hippocampal neurons. Neurofibrillary Tangles derived from intraneuronal infection by Borrelia in the model of SSPE dementia with Alzheimer's tangles in a childhood viral infection dementia. |
| Paper #5 Medical Hypotheses -- Alzheimer's Neuroborreliosis with Trans synaptic Spread of Infection and Neurofibrillary tangles derived from intraneuronal spirochetes Click here for Abstract |
| "invasion of human neuronal and glial cells by an infectious Strain of Borrelia burgdorferi Microbes and Infection In press Sept 2006Images of infected cells with Annotations - Click here |
| Biofilms of Borrelia burgdorferi Lecture - Click Here for Lecture and images July 7,2008 University of New Haven |
| Click here Alzheimer/Borrelia Molecular Interrogation project 1985 Quality controls and experimental protocol Agarose Gel Electrophoresis of PCR products DNA extracts - fresh Alzheimer disease autopsy Hippocampus slices obtained from Harvard Medical School McLean Hospital Brain Bank |
| Thank you very much for visiting this site The Research support has been provided by Turn the Corner Foundation, New York ,NY and St Catherine of Siena Medical Center, Smithtown, New York |
| Dot like forms of Malaria Parasites are called Merozoites (see position #26) These are the smallest form of the Malaria parasite- Note the diverse forms which malaria parasites demonstrate - in a Life Cycle In like manner the diverse forms of Borrelia spirochetes Spiral/corkscrew, granular dot, Cysts and L forms constitute a Life cycle |
| Granular (dotlike) spirochetal forms are the spirochetal equivalent of Merozoites |
Link to Medical
Hypotheses
Website
--Transfection DNA - first report of
Borrelia to Human Transfection with 7
patients showing Flagellin B DNA
inserts in Human Chromosome 11q
site
--Plaques of Alzheimer's derived from
Cysts of Borrelia by In Situ DNA
hybridization evidence
--Cyst forms of Borrelia as Unifying
concept for
Parkinson';s , ALS, Pick's, and other
Tauopathies
Click Here
Hypotheses
Website
--Transfection DNA - first report of
Borrelia to Human Transfection with 7
patients showing Flagellin B DNA
inserts in Human Chromosome 11q
site
--Plaques of Alzheimer's derived from
Cysts of Borrelia by In Situ DNA
hybridization evidence
--Cyst forms of Borrelia as Unifying
concept for
Parkinson';s , ALS, Pick's, and other
Tauopathies
Click Here
| Research papers (6)--Click here Medical Hypotheses - Draft versions with images obtain all 6 papers in one PDF File |
Lateral DNA Transfer Articles
and Monograph
lick here for review article
Click here for article on
mechanisms of DNA transfer
and Monograph
lick here for review article
Click here for article on
mechanisms of DNA transfer
Many Images presented on this
site-
are Copyright - by
Other Authors , and other
Publishers
and by
Alan B. Macdonald MD
site-
are Copyright - by
Other Authors , and other
Publishers
and by
Alan B. Macdonald MD
| Borrelia Attack Models Lecture May 19 2007 University of New Haven Images from Powerpoint Click Here to view |
Cases 2,3,4,5,6,7
Links to NCBI database files
DQ188100.1
DQ188101.1
DQ188102.1
DQ188103.1
DQ188104.1
DQ188105.1
Links to NCBI database files
DQ188100.1
DQ188101.1
DQ188102.1
DQ188103.1
DQ188104.1
DQ188105.1
| Click Here for Images of Biofilms of Borrelia burgdorferi Biofilms of Borrelia burgdorferi in human tissue -An Explanation of microbial persistence in the Human host > Chronic Lyme borreliosis is a biofilm infection |
| Click here for Dr P. Collart manuscript (in French) illustration of Granular and Cystic forms of Treponema Pallidum Biology of syphilis in French |
| Granular forms of Treponema spirochetes are dot-like particles which can regenerate the entire corkscrew shaped forms Click here to see granular forms |
| Granular forms of Treponema spirochetes are dot-like particles which can regenerate the entire corkscrew shaped forms Click here to see granular forms |
| Biofilms of Borrelia Burgdorferi in Chronic Cutaneous Borreliosis American Journal of Clinical Pathology 2008 |
Click here for full text
and graphics
2008 Paper - "Persisting
atypical and cystic forms of
Borrelia burgdorferi and
local inflammation in Lyme
Neuroborreliosis"
Dr. Judith Miklossy and
colleagues
and graphics
2008 Paper - "Persisting
atypical and cystic forms of
Borrelia burgdorferi and
local inflammation in Lyme
Neuroborreliosis"
Dr. Judith Miklossy and
colleagues
| Granular forms of Treponema spirochetes are dot-like particles which can regenerate the entire corkscrew shaped forms Click here to see granular forms |
| Borrelia Cystic form--- DNA In Situ Hybridization method for staining- Autopsy Case study- Diffuse Lewy body Dementia --Click here to view |
Concurrent Neocortical Borreliosis and
Alzheimer's disease - Human Pathology
1987
Concurrent Neocortical Borreliosis and
Alzheimer's disease - II- Demonstration
of a Spirochetal Cyst Form - Annals of
the New York Academy of Sciences
Click here1987 and 1989 papers on
Concurrent Neocortical Borreliosis and
Alzheimer's
Alzheimer's disease - Human Pathology
1987
Concurrent Neocortical Borreliosis and
Alzheimer's disease - II- Demonstration
of a Spirochetal Cyst Form - Annals of
the New York Academy of Sciences
Click here1987 and 1989 papers on
Concurrent Neocortical Borreliosis and
Alzheimer's
| cell wall deficient forms of Borrelia burgdorferi Click here to see images |
| Discussion of Cystic Spirochetes as links to Pick bodies Lewy bodies ALS Spherical Bodies Alzheimer Plaques |
Transfection (Lateral DNA transfer)
Borrelia to Human Alzheimer DNA
Data
Borrelia to Human Alzheimer DNA
Data